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AICAR phosphate
CAS No. 681006-28-0
AICAR phosphate ( Acadesine phosphate;AICA Riboside phosphate )
Catalog No. M15598 CAS No. 681006-28-0
AICAR phosphate (Acadesine, AICA Riboside, NSC 105823) is a selective AMPK activator in both hepatocytes and adipocytes.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameAICAR phosphate
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NoteResearch use only, not for human use.
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Brief DescriptionAICAR phosphate (Acadesine, AICA Riboside, NSC 105823) is a selective AMPK activator in both hepatocytes and adipocytes.
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DescriptionAICAR phosphate (Acadesine, AICA Riboside, NSC 105823) is a selective AMPK activator in both hepatocytes and adipocytes; inhibits the synthesis of fatty acids and sterols and inactivates HMG-CoA reductase in rat hepatocytes at 0.5 mM, inhibits insulin-stimulated glucose and reduces GLUT4 translocation in 3T3-L1 adipocytes; down-regulates the insulin receptor expression in HepG2 cells.
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SynonymsAcadesine phosphate;AICA Riboside phosphate
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PathwayMembrane Transporter/Ion Channel
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TargetAMPK
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RecptorAMPK
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Research AreaMetabolic Disease
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Indication——
Chemical Information
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CAS Number681006-28-0
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Formula Weight356.23
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Molecular FormulaC9H17N4O9P
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Purity>98% (HPLC)
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Solubility10 mM in H2O
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SMILESC1=NC(=C(N1C2C(C(C(O2)CO)O)O)N)C(=O)N.OP(=O)(O)O
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Chemical NameImidazole-4-carboxamide, 5-amino-1-ribosyl-, phosphate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Sullivan JE, et al. FEBS Lett. 1994 Oct 10;353(1):33-6.
2. Young ME, et al. FEBS Lett. 1996 Mar 11;382(1-2):43-7.
3. Samari HR, et al. J Biol Chem. 1998 Sep 11;273(37):23758-63.
4. Ayasolla KR, et al. J Neuroinflammation. 2005 Sep 20;2:21.
2. Young ME, et al. FEBS Lett. 1996 Mar 11;382(1-2):43-7.
3. Samari HR, et al. J Biol Chem. 1998 Sep 11;273(37):23758-63.
4. Ayasolla KR, et al. J Neuroinflammation. 2005 Sep 20;2:21.
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